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Miami is a sprawling metropolis containing a multitude of cultures and attractions. While that makes for an incredible trip, it can be tricky for first-timers to figure out the best place to base themselves.

It all depends on what you want to do and who you're traveling with. Are you downing cafecitos and cocktails before salsa dancing into the wee hours or kayaking and stretching out on a beautiful stretch of sand to relax? The best neighborhood for families is unlikely to have a thumping nightlife, but some areas offer a little bit of something for everyone.

Think about your must-do priorities in Magic City (if you're in need of inspiration, check out our favorite things to do there) and let our guide to Miami's neighborhoods help you choose the best possible base for your vacation.

1. Downtown Miami

Best neighborhood for an all-round taste of Miami (sans beach)

If you want to get a taste of nearly everything the city has to offer, Downtown Miami is ideal. Marvel at some of the city's most historic buildings, dating as far back as the 1890s – among them, the Olympia Theater (originally a silent movie theater) and the Freedom Tower (once a help center for Cuban refugees in the 1960s and 70s). Spend some time exploring and snapping photos, then learn more about the city's past at the HistoryMiami Museum.

But downtown is far from stuck in the past. Aside from the high rises, there are restaurants and retail to enjoy at Bayside Marketplace, plus boat tours on Biscayne Bay and that offers dazzling views of the neighborhood.

Fancy some culture? The Pérez Art Museum boasts a robust collection of art from Latin America and beyond, while the adjacent Frost Science Museum is home to a spectacular aquarium, planetarium and rotating exhibits. And if that's not enough, you can always see what's happening at the , home of the Miami Heat and a major entertainment venue.

2. Wynwood

Best neighborhood for art and design

Formerly known as Little San Juan, this once-heavily Puerto Rican neighborhood has undergone tremendous change, most notably because of gentrification. Today, it's an international hub of art, fashion and design. Brilliant murals adorn nearly every building facade, many of which were created by top street artists like Shepard Fairey and Atomik. Throw a stone in any direction, and you're sure to hit an art gallery, cocktail bar, vintage shop, uber-hip clothing boutique or even a taco shop that doubles as a speakeasy.

While there's a dearth of hotels in the area, you can book a room at the , or an Airbnb. Otherwise, venture into the neighborhood at your leisure and make a day of it by picking up an iced latte at Panther Coffee before wandering between the Wynwood Walls, and . The vibe changes to adults-only at night – enjoy a delicious meal at Kush or , then bar hop between , , Gramps or any other spot where the music's good.

3. South Beach

Best neighborhood for beach time and nightlife

Surely the most visited area of Miami, South Beach continues to draw crowds for several reasons. First, it's the best neighborhood for beach access no matter where you stay – many hotels offer private access and even those that don't often offer amenities like chairs and umbrellas. Traveling with kids? Stay near South Point Park – they'll love the splash pads and waving to outgoing cruise ships from the pier. Prefer something more lively? Anywhere along Ocean Drive or even Washington Ave is excellent.

Speaking of lively, the nightlife in South Beach is hard to beat. Popular staples like , and are always a good time, but feel free to branch out. is a small club with huge tunes delivered by guest DJs, while gives you that bass-all-over-your-body immersive party experience. And if dives are more your scene, you can't go wrong with a night at the infamous (if it was good enough for Anthony Bourdain, it's good enough for us).

Check out our favorite beaches – beyond South Beach

4. Little Havana

Best for immersing yourself in Latin American culture

Little Havana has plenty to offer in terms of culture and charm. Drive (or walk) along the infamous Calle Ocho, and you'll be greeted by giant, colorful rooster statues – a nod to the actual roosters that stroll about the area.

While there, check out the Cuban Walk of Fame to see the names of some of the biggest stars from the island nation. Follow up with a visit to the Cubaocho Museum for some history lessons as well as a chance to peruse art.

But the best thing about Little Havana? Hands down the opportunity to enjoy so many tasty dishes. Yes, this is understandably the best spot for Cuban cuisine and from to , to – it's all delicious. But it's not just Cuban food on the menu – try Salvadoran food at , Nicaraguan food at or Yambo, or stop at for Honduran fare. Your tastebuds will thank you.

5. Coconut Grove

Best neighborhood for seeing old-school Miami

If you'd like to experience some of Miami's lesser-known gems, spend some time in Coconut Grove. Quieter than SoBe but still plenty lively, the Grove is Miami's oldest neighborhood. Take a glimpse into the city's past at Barnacle Historic State Park (built in 1891, at a time when Miami was only accessible by boat).

Another must-see attraction is Vizcaya Museum & Gardens – this stunning waterfront villa, built in 1916, will make you feel like you've been transported to the Mediterranean. And if the weather's right, a stroll through the verdant Kampong Botanical Garden is a must.

Wander over to CocoWalk to experience the modern side of the Grove, an open-air center with boutique shops, restaurants, bars, a movie theater and more. While much of this area has been revamped in recent years, many beloved old staples are still around: delightful French bistro , GreenStreet Cafe (known for their incomparable brunches), and (popular drinking holes), t (perfect for healthy food options) and (an excellent taqueria that's open late). Make sure you check the calendar because the Grove hosts all kinds of fun events, from farmer's markets to open-air concerts.

6. Key Biscayne

Best for families seeking a low-key vacation

If you're looking for a relaxing beach getaway with the kids, you simply can't go wrong with Key Biscayne. It's like a little world unto itself, with just one major road to get from one end to the other. Accommodations aren't plentiful – the Ritz Carlton is one of the few hotels in the area – but there are always Airbnbs available for the whole family (and you can still visit the Ritz for spa time).

Once there, you can divide your time between Crandon Park and Bill Baggs Cape Florida State Park. The former features one of the city's best Nature Centers, a mangrove boardwalk, guided hikes, plus plenty of space to enjoy the beach. Kiteboarding, kayaking and other eco-adventure tours are also available here.

The beaches at Bill Baggs are just as lovely, with opportunities to explore the on-site lighthouse, as well as go fishing, hiking, swimming, paddling and biking (single and quad bikes are available for rent). And if you're traveling with a four-legged friend, nearby Hobie Beach (near adjacent Virginia Key) is also a great place to spend a few hours.

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